Mechanosensitivity Is a Characteristic Feature of Cultured Suburothelial Interstitial Cells of the Human Bladder

Mechanosensitivity Is a Characteristic Feature of Cultured Suburothelial Interstitial Cells of the Human Bladder

Bladder dysfunction is characterised by urgency, frequency (pollakisuria, nocturia), and dysuria and should result in urinary incontinence. Most of those signs may be attributed to disturbed bladder sensitivity. There’s rising proof that, moreover the urothelium, suburothelial interstitial cells (suICs) are concerned in bladder afferent sign processing.

The large growth of the bladder throughout the filling section implicates mechanical stress delivered to the entire bladder wall. Little is understood concerning the response of suICs upon mechanical stress. Due to this fact, we investigated the results of mechanical stimulation in cultured human suICs. We used fura-2 calcium imaging as a serious physiological readout. We discovered spontaneous intracellular calcium exercise in 75 % of the aesthetic suICs. Outlined native stress software by way of a glass micropipette led to native elevated calcium exercise in all stimulated suICs, spreading over the entire cell.

A complete of 51% of the neighboring cells in a radius of as much as 100 µm from the stimulated cell confirmed an elevated exercise. Hypotonic ringer and shear stress additionally induced calcium transients. We discovered an 18-times enhance in syncytial exercise in comparison with unstimulated controls, leading to an amplification of the first calcium sign elicited in single cells by 50%.

Our outcomes converse in favor of a excessive sensitivity of suICs for mechanical stress and help the view of a practical syncytium between suICs, which may amplify and distribute native stimuli. Earlier research of connexin expression within the human bladder recommend that this mechanism is also related in regular and pathological operate of the bladder in vivo.

 

Totally Built-in Time-Gated 3D Fluorescence Imager for Deep Neural Imaging

This paper presents a tool for time-gated fluorescence imaging within the deep mind, consisting of two on-chip laser diodes and 512 single-photon avalanche diodes (SPADs). The sting-emitting laser diodes ship fluorescence excitation above the SPAD array, parallel to the imager. Within the time area, laser diode illumination is pulsed and the SPAD is time-gated, permitting a fluorescence excitation rejection as much as O.D. three at 1 ns of time-gate delay.

Every SPAD array is masked with Talbot gratings to allow the mapping of 2D array photon counts right into a 3D picture. The 3D picture achieves a decision of 40, 35, and 73 m within the x, y, z instructions, respectively, in a noiseless atmosphere, with a most body price of 50 kilo-frames-per-second. We current measurement outcomes of the spatial and temporal profiles of the dual-pulsed laser diode illumination and of the photon detection traits of the SPAD array. Lastly, we present the imager’s means to resolve a glass micropipette full of purple fluorescent microspheres. The system’s 420 m-wide cross part permits it to be inserted at arbitrary depths of the mind whereas reaching a subject of view 4 occasions bigger than fiber endoscopes of equal diameter.

Cytoskeleton consists of greater than 100 proteins and represents a dynamic community of the mobile cytoplasm. Cytoskeletal features embrace spatial group of mobile parts, structural connection of the cell with exterior atmosphere, and biomechanical power era. Cytoskeleton takes half, at totally different ranges, in all phases of platelet biogenesis: megakaryocyte (MK) differentiation, MK maturation, and platelet formation. As well as, it additionally performs a serious function in every stage of platelet operate.

Inherited platelet problems (IPDs) are a bunch of uncommon illnesses featured by low platelet rely and/or impaired platelet operate.

 Mechanosensitivity Is a Characteristic Feature of Cultured Suburothelial Interstitial Cells of the Human Bladder
Mechanosensitivity Is a Characteristic Feature of Cultured Suburothelial Interstitial Cells of the Human Bladder

Sublethal mechanical shear stress will increase the elastic shear modulus of purple blood cells however doesn’t change capillary transit velocity

Blood publicity to supraphysiological shear stress inside mechanical circulatory help is suspected of lowering purple blood cell (RBC) deformability and being primal within the pathogenesis of a number of secondary problems. No prior works have explored RBC dynamics with the decision required to find out shear elastic modulus, and/or cell capillary velocity, following publicity to mechanical stresses. Wholesome RBCs had been uncovered to 0,5,50, and 100Pa in a Couette shearing system.

For comparability, blood was additionally uncovered to warmth therapy – a technique that predictably will increase RBC rigidity. Shear modulus evaluation required aspiration of single RBCs by way of slender micropipettes at identified suction power. Cell transit velocities had been measured inside micro-channels in areas of fully-developed move. Supraphysiological shear stress elevated the elastic shear modulus by 39% and 69% following publicity to 50 and 100Pa, respectively.

Cell transit velocity, nevertheless, didn’t change following shear, with concurrent decreases in cell quantity probably nullifying elevated shear modulus-friction interactions. Variations noticed had been according to our inner management (warmth therapy), supporting that cell mechanics are considerably impaired following supraphysiological-sublethal shear publicity.

AXYPET 50-300UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X10

AP-8-300-STD 1/pk
EUR 507
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 5-50UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X4

AP-8-50-ALT 1/pk
EUR 456
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 5-50UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X10

AP-8-50-STD 1/pk
EUR 507
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 0.5-10UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X4

AP-8-10-ALT 1/pk
EUR 456
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 0.5-10UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X10

AP-8-10-STD 1/pk
EUR 507
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 20-200UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X4

AP-8-200-ALT 1/pk
EUR 456
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 20-200UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X10

AP-8-200-STD 1/pk
EUR 507
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Individual Reaction Mix 8

G065-8 200 reactions
EUR 167

Jade Smart? Mix-iCycler

M1114-500
EUR 441

Jade Smart? Mix-ROX

M1116-500
EUR 441

Smart Personal Micro Centrifuge

abx725002-1Unit 1 Unit
EUR 519

Human IL-8 Recombinant Protein

R00423-8 5ug/vial
EUR 259
Description: Interleukin-8 (IL-8), also known as CXCL8, is an ELR-positive CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. Human IL-8 Recombinant Protein is purified interleukin-8 produced in yeast.

AXYGEN® AXYPET® PRO 30-300 ΜL, 8 CHANNEL PIPETTOR, AUTOCLAVABLE

AP-8-300-P 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYGEN® AXYPET® PRO 5-50 ΜL, 8 CHANNEL PIPETTOR, AUTOCLAVABLE

AP-8-50-P 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYGEN® AXYPET® PRO 0.5-10 ΜL, 8 CHANNEL PIPETTOR, AUTOCLAVABLE

AP-8-10-P 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYGEN® AXYPET® PRO 20-200 ΜL, 8 CHANNEL PIPETTOR, AUTOCLAVABLE

AP-8-200-P 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Jade Smart? Mix-Low ROX

M1115-500
EUR 441

8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

DLR-8-OHdG-Ge-48T 48T
EUR 469
Description: A competitive inhibition quantitative ELISA assay kit for detection of 8-Hydroxydeoxyguanosine (8-OHdG) in samples from serum, plasma or other biological fluids.

8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

DLR-8-OHdG-Ge-96T 96T
EUR 608
Description: A competitive inhibition quantitative ELISA assay kit for detection of 8-Hydroxydeoxyguanosine (8-OHdG) in samples from serum, plasma or other biological fluids.

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RD-8-OHdG-Ge-48Tests 48 Tests
EUR 467

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RD-8-OHdG-Ge-96Tests 96 Tests
EUR 646

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RDR-8-OHdG-Ge-48Tests 48 Tests
EUR 488

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RDR-8-OHdG-Ge-96Tests 96 Tests
EUR 676

pAAV-DJ/8 Vector

VPK-420-DJ-8 10 µg
EUR 647
Description: The pAAV-DJ/8 vector contains the rep and cap genes required to generated recombinant AAV of serotype DJ/8. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-DJ/8 packaging.

Smart 2X PCR pre-mix Pfu (30ul)

9K-002-0038 30uL, 30uL
EUR 581.14

Transmembrane Channel Like 8 (TMC8) Antibody

abx027907-400ul 400 ul
EUR 523

Transmembrane Channel Like 8 (TMC8) Antibody

abx027907-80l 80 µl
EUR 286

Transmembrane Channel Like 8 (TMC8) Antibody

20-abx219015
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Transmembrane Channel Like 8 (TMC8) Antibody

20-abx329114
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

PSA (Prostate-specific antigen) ELISA test

8 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PSA (Prostate-specific antigen)

ASPIR-8, 5ml reservoir for 8-channel pipettes, individually wrapped

P7005-1S 100/pack
EUR 99.95
Description: ASPIR-8 5ml reservoir for 8-channel pipettes

ASPIR-8, 25ml reservoir for 8-channel pipettes, individually wrapped

P7025-1S 100/pack
EUR 99.95
Description: ASPIR-8 25ml reservoir for 8-channel pipettes

ASPIR-8, 10ml reservoir for 8-channel pipettes, individually wrapped

P8010-1S 100/pack
EUR 99.95
Description: ASPIR-8 10ml reservoir for 8-channel pipettes

AAV-DJ/8 Helper Free Packaging System

VPK-400-DJ-8 1 kit
EUR 972
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-DJ/8 Helper Free Expression System

VPK-410-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

scAAV-DJ/8 Helper Free Expression System

VPK-430-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

PIPETTOR,8 CHANNEL,20-200UL,1 EA

4888 1/pk
EUR 849
Description: Corning Liquid Handling Equipment; Costar 8 Pette and 12 Pette Multichannel Pipettors

ELISA Microplate Washer Head (8 channel) replacement

MPW-WH-1 1
EUR 354

AAV-DJ/8 Helper Free Promoterless Expression System

VPK-411-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

ASPIR-8, 5ml reservoir for 8-channel pipettes, 5/sterile bag

P7005-5S 200/pack
EUR 116.15
Description: ASPIR-8 5ml reservoir for 8-channel pipettes

ASPIR-8, 25ml reservoir for 8-channel pipettes, 5/sterile bag

P7025-5S 200/pack
EUR 116.15
Description: ASPIR-8 25ml reservoir for 8-channel pipettes

ASPIR-8, 10ml reservoir for 8-channel pipettes, 5/sterile bag

P8010-5S 200/pack
EUR 116.15
Description: ASPIR-8 10ml reservoir for 8-channel pipettes

General 8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a) ELISA Kit

RD-8-epi-PGF2a-Ge-48Tests 48 Tests
EUR 467

General 8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a) ELISA Kit

RD-8-epi-PGF2a-Ge-96Tests 96 Tests
EUR 646

AXYGEN® 8-WELL COMB FOR USE WITH 10 CM GEL BOX, 1.0 MM THICKNESS

HGB10-8-1 1/pk
EUR 59
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.0 MM THICKNESS

HGB15-8-1 1/pk
EUR 69
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-8-15 1/pk
EUR 69
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 7 CM GEL BOX, 0.75 MM THICKNESS

HGB7-8-075 1/pk
EUR 54
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 7 CM GEL BOX, 1.0 MM THICKNESS

HGB7-8-1 1/pk
EUR 54
Description: Lab Equipment; Axygen Branded EQ

AAV-DJ/8 Helper Free Bicistronic Expression System (Puro)

VPK-415-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (Neo)

VPK-416-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (Hygro)

VPK-417-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (GFP)

VPK-418-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (Blasticidin)

VPK-419-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

MINI TUBE, 8 STRIP, POLYPROPYLENE, 1.1 ML, CLEAR, NONSTERILE, BULK

MTS-11-8-C 120/pk
EUR 140
Description: Deep Well/Assay Plates - Axygen; Assay/Other - Axygen

ASPIR-8, 5ml reservoir for 8-channel pipettes, non-sterile, bulk pack

P7005 300/pack
EUR 108.05
Description: ASPIR-8 5ml reservoir for 8-channel pipettes

ASPIR-8, 25ml reservoir for 8-channel pipettes, non-sterile, bulk pack

P7025 100/pack
EUR 79.7
Description: ASPIR-8 25ml reservoir for 8-channel pipettes

ASPIR-8, 10ml reservoir for 8-channel pipettes, non-sterile, bulk pack

P8010 300/pack
EUR 108.05
Description: ASPIR-8 10ml reservoir for 8-channel pipettes

LAMBDA PLUS PIPETTOR 8 CHANNEL,1 TO 10UL

4080 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Multi-Channel Pipettors

LAMBDA PLUS PIPETTOR 8 CHANNEL,5 TO 50UL

4081 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Multi-Channel Pipettors

LAMBDA PLUS PIPETTOR 8 CHANNEL,20 TO 200UL

4082 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Multi-Channel Pipettors

LAMBDA PLUS PIPETTOR 8 CHANNEL,50 TO 300UL

4083 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Multi-Channel Pipettors

ProPette LE 8-Channel Pipette, 1 to 10µL

P5208-10 1/pack
EUR 319.33
Description: ProPette LE 8-Channel Pipette 1 to 10µL

ProPette LE 8-Channel Pipette, 2 to 20µL

P5208-20 1/pack
EUR 319.33
Description: ProPette LE 8-Channel Pipette 2 to 20µL

ProPette LE 8-Channel Pipette, 20 to 200µL

P5208-200 1/pack
EUR 319.33
Description: ProPette LE 8-Channel Pipette 20 to 200µL

ProPette LE 8-Channel Pipette, 30 to 300µL

P5208-300 1/pack
EUR 319.33
Description: ProPette LE 8-Channel Pipette 30 to 300µL

ProPette LE 8-Channel Pipette, 5 to 50µL

P5208-50 1/pack
EUR 319.33
Description: ProPette LE 8-Channel Pipette 5 to 50µL

Mouse Transmembrane channel- like protein 8, Tmc8 ELISA KIT

ELI-51686m 96 Tests
EUR 865

Human Transmembrane channel- like protein 8, TMC8 ELISA KIT

ELI-36423h 96 Tests
EUR 824

Voltage-Dependent Calcium Channel Gamma-8 Subunit (CACNG8) Antibody

20-abx148797
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

8 channel ph/ec/sal/tds/res/ion meter

C3060 ea
EUR 1620

8 channel ph/ec/sal/tds/res/do meter

C3062 ea
EUR 1620

Sodium Channel Protein Type 8 Subunit Alpha (SCN8A) Antibody

20-abx135926
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

TRANSTAR DISPOSABLE RESERVOIR LINER,8-CHANNEL,NS,BK100/100

94878 100/pk
EUR 265
Description: Corning Liquid Handling Equipment; Transtar

CORNING 5-50 µL LAMBDA ELITETOUCH 8 CHANNEL PIPETTOR

6058 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Multi-Channel Pipettors

CORNING 20-200 µL LAMBDA ELITETOUCH 8 CHANNEL PIPETTOR

6059 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Multi-Channel Pipettors

CORNING 30-300 µL LAMBDA ELITETOUCH 8 CHANNEL PIPETTOR

6060 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Multi-Channel Pipettors

MULTICHANNEL PIPETTE STAND FOR 8 OR 12 CHANNEL PIPETTORS

4088 1/pk
EUR 57
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Multi-Channel Pipettors

Sodium Channel Protein Type 8 Subunit Alpha (SCN8A) Antibody

20-abx321273
  • EUR 439.00
  • EUR 328.00
  • 100 ul
  • 50 ul

Sodium Channel Protein Type 8 Subunit Alpha (SCN8A) Antibody

20-abx322781
  • EUR 439.00
  • EUR 328.00
  • 100 ul
  • 50 ul

UNIVERSAL LINEAR STAND FOR FOUR PIPETTORS, ORANGE (FOUR SINGLE-CHANNEL, MAXIMUM OF TWO 8-CHANNEL OR 12-CHANNEL PIPETTORS)

6066 1/pk
EUR 69
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Single Channel Pipettors

UNIVERSAL LINEAR STAND FOR FOUR PIPETTORS, TRANSPARENT (FOUR SINGLE-CHANNEL, MAXIMUM OF TWO 8-CHANNEL OR 12-CHANNEL PIPETTORS)

6067 1/pk
EUR 69
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Single Channel Pipettors

UNIVERSAL LINEAR STAND FOR SIX PIPETTORS, TRANSPARENT (SIX SINGLE-CHANNEL, MAXIMUM OF THREE 8-CHANNEL OR 12-CHANNEL PIPETTORS)

6068 1/pk
EUR 85
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Single Channel Pipettors

MINI TUBE, 8 STRIP, POLYPROPYLENE, 1.1 ML, CLEAR, RACKED, NONSTERILE, BULK

MTS-11-8-C-R 120/pk
EUR 280
Description: Deep Well/Assay Plates - Axygen; Assay/Other - Axygen

Potassium Voltage-Gated Channel Subfamily J Member 8 (KCNJ8) Antibody

20-abx126036
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Potassium Voltage-Gated Channel Subfamily J Member 8 (KCNJ8) Antibody

20-abx114635
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Potassium Voltage-Gated Channel Subfamily J Member 8 (KCNJ8) Antibody

abx026711-400ul 400 ul
EUR 523

Potassium Voltage-Gated Channel Subfamily J Member 8 (KCNJ8) Antibody

abx026711-80l 80 µl
EUR 286

Potassium Voltage-Gated Channel Subfamily J Member 8 (KCNJ8) Antibody

20-abx216389
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Potassium Voltage-Gated Channel Subfamily H Member 8 (KCNH8) Antibody

20-abx213679
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Potassium Voltage-Gated Channel Subfamily H Member 8 (KCNH8) Antibody

20-abx214495
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Potassium Voltage-Gated Channel Subfamily J Member 8 (KCNJ8) Antibody

20-abx334148
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Paraffin Tissue Section - Human Bone Tumor: Synovial Sarcoma

T2235023-8 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Brain Tumor: Malignant Oligodendroglioma

T2235035-8 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Colon Tumor: Diffuse Type Non-Hodgkin's Lymphoma

T2235090-8 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Skin Tumor: Squamous Cell Carcinoma , Well Differentiated

T2235218-8 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

DiscoveryPak™ Antiviral Agents Set

S252-8 8 antiviral agents
EUR 839

Custom siRNA

M1253-8
EUR 495

Chemically Modified siRNA

M1254-8
EUR 539

Fluorescent labeled siRNA

M1255-8
EUR 615

ss miRNA mimics

M1259-8
EUR 495

ds miRNA mimics

M1262-8
EUR 495

miRNA Inhibitor

M1265-8
EUR 495

DiscoveryPak? Stem Cell Fate Regulator Set II

K853-8
EUR 1088

DiscoveryPak? Receptor Tyrosine Kinase (RTK) Inhibitor Set

K859-8
EUR 778

PathwayReady? JAK/STAT Signaling Inhibitor Panel

K864-8
EUR 947

DiscoveryPak? Neuronal Cell Induction Small Molecules Set

K892-8
EUR 914

DiscoveryPak? Detergents Set I

S226-8
EUR 523

DiscoveryPak? GSK-3 Inhibitors Set

S237-8
EUR 805

Blocking Solution

K2191050-8 250 ul
EUR 137
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Anti-GFAP Antibody (monoclonal, 3F2)

M00213-8 100ug/vial
EUR 334

Anti-Caspase-3 Rabbit Monoclonal Antibody, Clone#RM250

M00334-8 100ul
EUR 375
Description: Anti-Caspase-3 Rabbit Monoclonal Antibody, Clone#RM250 tested in WB, IHC, reactive to Human

Protein A Agarose Resin

BSP095-8 5ml
EUR 245.75

Anti-Acetyl-Histone H3 (Lys36) Rabbit Monoclonal Antibody, Clone#RM154

M06819-8 100ug
EUR 478
Description: Anti-Acetyl-Histone H3 (Lys36) Rabbit Monoclonal Antibody, Clone#RM154 tested in WB, ELISA, Multiplex, ICC, reactive to All Vertebrates

Anti-Histone H3 (mono+di+tri methyl K79) Rabbit Monoclonal Antibody

M12477-8 100ug/vial
EUR 397
Description: Anti-Histone H3 (mono+di+tri methyl K79) Rabbit Monoclonal Antibody tested for IHC, WB in Human, Mouse, Rat

Anti-Acetyl-Histone H4 (Lys16) Rabbit Monoclonal Antibody, Clone#RM204

M14495-8 100ug
EUR 468
Description: Anti-Acetyl-Histone H4 (Lys16) Rabbit Monoclonal Antibody, Clone#RM204 tested in WB, ELISA, Multiplex, reactive to All Vertebrates

PYREX® 8X8MM CLONING CYLINDERS

3166-8 125/pk
EUR 72
Description: Dishes; Clonig Dish/Cyl

Human TNF alpha Recombinant Protein

R00002-8 5ug/vial
EUR 259
Description: Tumor necrosis factor alpha (TNFSF2, TNF alpha) is a member of the TNF Superfamily. TNF alpha, being an endogenous pyrogen, is able to induce fever, to induce apoptotic cell death, to induce sepsis (through IL-1 & IL-6 production), to induce cachexia, induce inflammation, and to inhibit tumorigenesis and viral replication. Human TNF alpha Recombinant Protein is purified TNF alpha (TNFSF2) produced in yeast.

Swine VEGF-A Recombinant Protein

R00045-8 5ug/vial
EUR 259
Description: VEGF-A is member of the family of vascular endothelial growth factor (VEGF) proteins, which stimulate vasculogenesis and angiogenesis to restore oxygen supply to tissues. VEGF-A is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor (VPF). Swine VEGF-A Recombinant Protein is purified vascular endothelial growth factor A produced in yeast.

Ovine IL-1 beta Recombinant Protein

R00101-8 5ug/vial
EUR 259
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Ovine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.

Swine IL-6 Recombinant Protein

R00102-8 5ug/vial
EUR 259
Description: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. Swine IL-6 Recombinant Protein is purified interleukin-6 produced in yeast.

Swine IL-4 Recombinant Protein

R00230-8 5ug/vial
EUR 259
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Swine IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

Swine CXCL10 Recombinant Protein

R00278-8 5ug/vial
EUR 259
Description: The ELR-negative CXC chemokine CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. Swine CXCL10 Recombinant Protein is purified CXCL10 (IP-10) produced in yeast.

Rabbit IL-2 Recombinant Protein

R00387-8 5ug/vial
EUR 259
Description: Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. Rabbit IL-2 Recombinant Protein is purified interleukin-2 produced in yeast.

Mouse IFN gamma Recombinant Protein

R00393-8 5ug/vial
EUR 259
Description: IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Mouse IFN gamma Recombinant Protein is purified IFN gamma produced in yeast.

Swine IL-17A Recombinant Protein

R00421-8 5ug/vial
EUR 259
Description: IL-17A is a member of the IL-17 family of cytokines, whose members are involved in numerous immune regulatory functions. IL-17 induces the production of many other cytokines, chemokines, and prostaglandins. Swine IL-17A Recombinant Protein is purified interleukin-17A produced in yeast.

VEGF (121 a.a.), Vascular Endothelial Growth Factor-121 Human Recombinant Protein, His Tag

PROTP15692-8 Regular: 10ug
EUR 317
Description: Vascular Endothelial Growth Factor-121 Human Recombinant produced in E.Coli is a double, non-glycosylated, polypeptide chain (aa 207-327) containing a total of 142 amino acids and having a molecular mass of 16.3 kDa. ;The VEGF-121 is fused to a 20 amino acid His tag at N-terminus and purified by proprietary chromatographic techniques.

SNCA Alpha Synuclein Human Recombinant Protein

PROTP37840-8 Regular: 100ug
EUR 317
Description: a-Synuclein Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain of 140 amino acids having a molecular mass of 14.4kDa (Real molecular weight on SDS-PAGE will be shift up).  ;The Recombinant Human a-Synuclein is purified by proprietary chromatographic techniques.

SPA Staphylococcal Protein-A Long Form Recombinant Protein

PROTP38507-8 Regular: 100mg
EUR 418
Description: SPA Recombinant Long Form produced in E.Coli is a single non-glycosylated polypeptide chain. SPA Long Form is comprised of 5 IgG-binding domains E-D-A-B-C aligned in series containing 422 amino acids (including a.a 273-400 from acc# P99134) and having a molecular mass of 46.6kDa containing little or no carbohydrate.

Recombinant Human PlGF-2 Protein

PROTP49763-8 25ug
EUR 317
Description: PLGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PLGF-2 is expressed in umbilical vein endothelial cells and placenta. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. PlGF-2 also signals through Neuropilin (NP-1) and can bind with high affinity to heparin. Recombinant human PLGF-2 is a 34.0 kDa disulfide-linked homodimeric protein of two 150 amino acid polypeptide chains.

Acrp30 Human, Adiponectin glycosylated Human Recombinant Protein, HMW Rich

PROTQ15848-8 Regular: 10ug
EUR 317
Description: Adiponectin Human Recombinant HMW Rich produced in HEK cells is a single, glycosylated, polypeptide chain (19-244) containing a total of 226 amino acids, having a molecular mass of 24.6kDa (calculated). Human Acrp30 HMW Rich migrates on SDS-PAGE under non-reducing conditions at ~ 884 kDa.

ExoMS Surface Protein Capture Kit (Serum/Plasma EVs)

EXOMS101A-8 8 reactions
EUR 970

ExoMS Surface Protein Capture Kit (Tissue Culture EVs)

EXOMS111A-8 8 reactions
EUR 917

ExoMS Total Protein Capture Kit

EXOMS120A-8 8 reactions
EUR 477

Exo-Check Exosome Antibody Array

EXORAY210A-8 8 arrays
EUR 980

Exo-Check Exosome Antibody Array (Neuro) Standard

EXORAY500A-8 8 arrays
EUR 1159

Exo-Check Exosome Antibody Array (Neuro) Mini

EXORAY510A-8 8 arrays
EUR 773

Human ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E01A1896-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E01A1896-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E01A1896-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E02A1896-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E02A1896-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E02A1896-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E03A1896-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E03A1896-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E03A1896-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E04A1896-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E04A1896-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E04A1896-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E09A1896-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey ATP sensitive inward rectifier potassium channel 8(KCNJ8) ELISA kit

E09A1896-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey ATP sensitive inward rectifier potassium channel 8(KCNJ8) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Given mechanical circulatory help operates at shear stresses according to the current research, it’s believable that these units induce elementary impairment to the fabric properties of RBCs.

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